Migre-Lief ®
A Dietary Supplement Supporting Cerebrovascular Tone*

Formulated by leading researchers in the fields of natural medicine and nutrition, Migre-Lief®  is the first comprehensive supplement for the support of cerebrovascular tone.  Using a botanical extract and nutritional supplements in the amounts shown beneficial in scientific studies, Migre-Lief®  provides a valuable tool for patients seeking a dietary supplement to help support normal cerebrovascular tone.

Product Description

Migre-Lief® is a unique combination of herbal and nutritional supplements aimed at supporting cerebrovascular tone, and reducing platelet aggregation and the production of pro-inflammatory mediators.  The herbal and nutritional ingredients in Migre-Lief®  are used in the amounts shown to be beneficial in scientific studies.

• Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum parthenium) is rich in compounds known as sesquiterpene lactones.  The most important of these compounds is parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew leaf extracts.  Particularly important in feverfew extracts is the parthenolide content as well as the stability of this important constituent.  Migre-Lief®  is not only standardized to a high parthenolide content of 0.7% but also measures the stability of parthenolide.   Standardization insures the optimal dosage of parthenolide in an extract that will not lose its potency over time.  Scientific studies have found that parthenolide inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules.  It has also been shown to inhibit pro-inflammatory prostaglandin synthesis and the release of arachadonic acid.   European studies have shown the benefits of a feverfew extract, standardized on parthenolide content, on the long-term support of cerebrovascular tone.

• Magnesium is a nutritional supplement with numerous effects that support vascular tone.  These include:  1) inhibition of platelet aggregation;  2) interference with synthesis release, and action of inflammatory mediators;  3) direct alterations of cerebrovascular tone;  4) inhibition of vasospasm;  and  5) stabilization of cell membranes.  Some persons with poor cerebrovascular tone have been found to have low brain levels of magnesium.  Recommended daily dosages of magnesium typically range from 200 to 600 mg to compensate for this deficiency.

• Riboflavin (vitamin B-2) is a precursor of flavin adenine dinucleotide (FAD).  This coenzyme is an important component of the electron-transport chain.   A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone.  This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain.
  

Ingredients

Recommended Use

Take one caplet twice daily.  Migre-Lief®  is designed to provide benefits within four to six weeks.  Once results are noted, Migre-Lief®  may be used for several months as part of a daily supplement regime and comprehensive wellness program.

Contraindications, Adverse Reactions or Interactions

Side effects due to any of the ingredients in Migre-Lief®  are rare.   Mild gastrointestinal upset and loose stools may occur in some persons using magnesium.  This product is not recommended for use during pregnancy or lactation and should not be used in children under the age of two years.  Persons taking potassium-sparing diuretics or with renal failure should not use this product.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Locally Owned and Operated by Les and Maxine Wolff
1999 - 2006 © Wolff Drug & Variety -- All right reserved.

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